What are the criteria for 3B-NEO reporting results?

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  • 3B-NEO strictly follows the ACMG variant interpretation guidelines, the globally recognized gold standard in clinical genomics. 
  • Among the tens of thousands of variants identified during whole-genome analysis, only those with scientifically and clinically well-established disease associations classified as Pathogenic or Likely Pathogenic are selected for reporting. This minimizes confusion from uncertain findings and represents the optimal reporting standard to support clinicians in taking immediate, confident medical action.